Predictive value of the non-stress test for cesarean section and neonatal depression
DOI:
https://doi.org/10.59594/iicqp.2026.v4n1.155Keywords:
Apgar Score, Cesarean Section, Fetal Monitoring, Childbirth, ForecastingAbstract
Objective: To evaluate the predictive capacity of the non-stress test (NST) to determine the mode of delivery by cesarean section and Apgar scores at 1 and 5 minutes.
Methods: Quantitative, analytical diagnostic validity, non-experimental, and cross-sectional study conducted using NST results from 944 pregnant women attended at the electronic fetal monitoring service of a public hospital in Lima, Peru, during 2023. Live-born neonates whose mothers had a conclusive NST were included, excluding cases with congenital malformations or interrupted tests. Mathematical formulas were applied to calculate diagnostic validity measures and predictive values.
Results: The median maternal age was 29.0 years (IQR: 24.0–34.0). A total of 71.0% of NST results were reactive and 29.0% were non-reactive. Cesarean delivery predominated (52.2%). The NST showed a sensitivity of 27.4%, specificity of 69.2%, positive predictive value (PPV) of 49.3%, and negative predictive value (NPV) of 46.6% for predicting cesarean delivery. For an Apgar score <7 at 1 minute, the sensitivity of the NST was 36.1%, specificity 71.3%, PPV 4.7%, and NPV 96.6%. At 5 minutes, the sensitivity of the NST decreased to 16.7%, specificity to 70.9%, PPV to 0.4%, and NPV to 99.3%.
Conclusions: The NST shows limited sensitivity and PPV for determining the mode of delivery and initial neonatal depression based on the Apgar score. However, its high NPV supports its usefulness as a screening tool to rule out acute fetal compromise, always in combination with clinical and obstetric criteria within a comprehensive fetal assessment approach.
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1. Singh N, Pradeep Y, Jauhari S. Indications and Determinants of Cesarean Section: A Cross-Sectional Study. Int J Appl Basic Med Res. 2020;10(4):280-5. doi: 10.4103/ijabmr.IJABMR_3_20
2. Angolile CM, Max BL, Mushemba J, Mashauri HL. Global increased cesarean section rates and public health implications: A call to action. Health Sci Rep. 2023;6(5):e1274. doi: 10.1002/hsr2.1274
3. Ayres-de-Campos D, Simon A, Modi N, Tudose M, Saliba E, Wielgos M, et al. European association of perinatal medicine (EAPM) European midwives association (EMA) Joint position statement: Caesarean delivery rates at a country level should be in the 15-20 % range. Eur J Obstet Gynecol Reprod Biol. 2024;294:76-8. doi: 10.1016/j.ejogrb.2024.01.005
4. Instituto Nacional de Estadística e Informática. El 37,8% de los nacimientos registrados se dieron mediante cesárea en el año 2023 [Internet]. Lima: INEI; 2024 [citado el 15 de octubre de 2025]. Disponible en: https://www.gob.pe/institucion/inei/noticias/960252-el-37-8-de-los-nacimientos-registrados-se-dieron-mediante-cesarea-en-el-ano-2023
5. Martins ES, de Oliveira LD, Bessa Martins LF, Tavares LM, Costa Dos Santos MB, de Barros Neto M, et al. Healthcare, socioeconomic and obstetric factors associated with the excess of cesarean sections in 880,000 births from the city of Rio de Janeiro, Brazil. Sex Reprod Healthc. 2025;43:101068. doi: 10.1016/j.srhc.2025.101068
6. Umana OD, Vadakekut ES, Siccardi MA. Antenatal Fetal Surveillance. En: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025 [citado el 15 de octubre de 2025]. Disponible en: http://www.ncbi.nlm.nih.gov/books/NBK537123/
7. Nageotte MP. Fetal heart rate monitoring. Semin Fetal Neonatal Med. 2015;20(3):144-8. doi: 10.1016/j.siny.2015.02.002
8. American College of Obstetricians and Gynecologists. Antepartum Fetal Surveillance: ACOG Practice Bulletin, Number 229. Obstet Gynecol. 2021;137(6):e116-27. doi: 10.1097/AOG.0000000000004410
9. Rahman J, Begum HA. Prediction of Foetal Well-being with Non-stress Test. J Bangladesh Coll Physicians Surg. 2016;33(2):65-9. doi: 10.3329/jbcps.v33i2.28021
10. Joshi SK, Dangal G. Non Stress Test as a Predictor of Maternal and Fetal Outcome in Patients Presenting with Reduced Fetal Movement at Term. J Nepal Health Res Counc. 2022;20(1):21-5. doi: 10.33314/jnhrc.v20i01.3628
11. Lohana R, Khatri M, Hariharan C. Correlation of non stress test with fetal outcome in term pregnancy (37-42 Weeks). Int J Reprod Contracept Obstet Gynecol. 2013;2(4):639. doi: 10.5455/2320-1770.ijrcog20131229
12. Kaur N, Jindal P. Study of ‘Nonstress Test at Admission’ and its Correlation with Maternal and Fetal Outcome. J South Asian Fed Obstet Gynaecol. 2018;10(3):161-6. doi: 10.5005/jp-journals-10006-1581
13. Priya DR, Anushree A. Predictive accuracy of non-reactive NST for caesarean section for fetal distress. J Cardiovasc Dis Res [Internet]. 2023 [citado el 15 de octubre de 2025];14(9):1958-61. Disponible en: https://jcdronline.org/index.php/JCDR/article/view/12771
14. Amin H, Dashora S, Sharma R, Joshi R. Evaluation of non-stress test as predictor of perinatal outcome in high risk and low risk pregnancy: a prospective study. Int J Reprod Contracept Obstet Gynecol. 2023;12(8):2450-5. doi: 10.18203/2320-1770.ijrcog20232289
15. Flores-Salcedo L, García-Cajaleón J, Orozco-Elizondo LA, Guillen-Calle BE. Reactividad del test no estresante y su asociación con la puntuación Apgar neonatal: un análisis retrospectivo. Investig Innov Clin Quir Pediatr. 2025;3(1):6-12. doi: 10.59594/iicqp.2025.v3n1.129
16. Campbell HE, Ratushnyak S, Georgieva A, Impey L, Rivero-Arias O. Exploring the potential cost-effectiveness of a new computerised decision support tool for identifying fetal compromise during monitored term labours: an early health economic model. Cost Eff Resour Alloc. 2024;22(1):72. doi: 10.1186/s12962-024-00580-x
17. Perleche Ugás D, Aiquipa Zavala AM, Tuanama Alvarez MC. Condiciones de habitabilidad durante la pandemia por COVID-19: San Juan de Lurigancho, Lima-Perú. Bitacora Urb Terr. 2022;32(2):227-40. doi: 10.15446/bitacora.v32n2.99739
18. Solórzano Giraldo KE. Capacidad predictiva del test estresante en relación a los resultados perinatales en gestantes con embarazo a término atendidas en el instituto nacional materno perinatal. Lima, junio – agosto 2015 [Tesis de Licenciatura en Internet]. Lima: Universidad Nacional Mayor de San Marcos; 2016 [citado el 15 de octubre de 2025]. Disponible en: https://hdl.handle.net/20.500.12672/4754
19. Instituto Nacional Materno Perinatal. Guía de Práctica Clínica y de Procedimientos en Obstetricia y Perinatología 2018 [Internet]. Lima: INMP; 2018 [citado el 15 de octubre de 2025]. Disponible en: https://www.inmp.gob.pe/uploads/file/Revistas/Guias%20de%20Practica%20Clinica%20y%20de%20procedimientos%20en%20Obstetricia%20y%20Perinatologia%20del%202018.pdf
20. Laffita BA. Factores que influyen en el Apgar bajo al nacer, en el Hospital América Arias de La Habana, Cuba, 2000. Rev Chil Obstet Ginecol. 2005;70(6):359-63. doi: 10.4067/S0717-75262005000600002
21. Martinez Chipana JJ, Maldonado Condori MR. Relación entre hallazgos cardiotocográficos del test no estresante y resultados perinatales en gestantes a término, atendidas en el Centro de Salud Ciudad Nueva Junio 2021 – mayo 2022 [Tesis de Grado en Internet]. Tacna: Universidad Nacional Jorge Basadre Grohmann; 2024 [citado el 15 de octubre de 2025]. Disponible en: https://repositorio.unjbg.edu.pe/handle/20.500.12510/4700
22. Weinberger H, Nekave S, Hallak M, Naeh A, Gabbay-Benziv R. Single Sporadic Deceleration during Reactive Nonstress Test-Clinical Significance and Risk for Cesarean Delivery. J Clin Med. 2023;12(10):3387. doi: 10.3390/jcm12103387
23. Raghuwanshi D, Sarda G. Study of non-stress test (NST) as an admission test for maternal and fetal outcome in pregnancy beyond 32 weeks - prospective observational study at tertiary care center. Int J Med Pharm Res. 2024;6(2):10. doi: 10.5281/zenodo.13801367
24. Deshmukh S, Choudhary A, Jungari M, Jaiswal A. Study of Non-Stress Test as a Screening Tool in Low Risk Pregnancies at Term Gestation. Indian J Forensic Med Toxicol. 2020;14(4):7126-31. doi: 10.37506/ijfmt.v14i4.12768
25. Zeta Zeta A. Valor predictivo y razón de verosimilitud del test no estresante para la indicación de cesárea de emergencia en el Hospital Nacional Arzobispo Loayza – MINSA. Período 2018 [Trabajo Académico para Especialista en Internet]. Lima: Universidad Peruana Cayetano Heredia; 2019 [citado el 15 de octubre de 2025]. Disponible en: https://repositorio.upch.edu.pe/handle/20.500.12866/7236
26. Miranda R. Test no estresante en identificación de vía del parto en gestante de Alto Riesgo Obstétrico, Hospital de Cutervo - Cajamarca, 2022 [Tesis de Especialidad en Internet]. Huánuco: Universidad Nacional Hermilio Valdizán; 2024 [citado el 15 de octubre de 2025]. Disponible en: https://repositorio.unheval.edu.pe/item/3562100b-50e8-4640-9a0c-fb34e8c0dcd4
27. Rezaee M, Jahanshahifard S, Heidari SH. Association between Apgar score, umbilical artery cord pH and base excess in the first hour of birth in neonates. Nurs Midwifery J [Internet]. 2014 [citado el 15 de octubre de 2025];12(2):144-52. Disponible en: https://unmf.umsu.ac.ir/article-1-1833-en.html
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