Management and treatment of ovarian endodermal sinus tumor in a 14-year-old adolescent: a case report
Manejo y tratamiento del tumor del seno endodérmico de ovario en adolescente de 14 años: reporte de caso
##plugins.themes.bootstrap3.article.main##
Malignant tumors in adolescence are rare, and they are usually of germinal origin. Specifically, endodermal sinus tumors of the ovary are exceptional in this population. In this case report, we present a 14-year-old adolescent diagnosed with this type of tumor in her right ovary at the Gynecology Service of the Instituto Nacional de Salud del Niño San Borja, Lima, Peru. This case is the first of its kind in the institution, and no similar cases have been reported in our country, underscoring its significance. The patient had a large mixed tumor of 1470 grams, detected through pelvic magnetic resonance imaging. Tumor markers allowed a presumptive diagnosis of a probably malignant ovarian tumor. As a result, the patient underwent laparotomy, unilateral salpingo-oophorectomy, frozen biopsy, and staging. Subsequently, the patient received chemotherapy with good results, and alpha-fetoprotein levels normalized during followup.
Downloads
##plugins.themes.bootstrap3.article.details##
Brown MF, Hebra A, McGeehin K, Ross AJ 3rd. Ovarian masses in children: a review of 91 cases of malignant and benign masses. J Pediatr Surg. 1993;28(7):930-3. doi: 10.1016/0022-3468(93)90700-u
Fabbro MA, Costa L, Spata E, Cimaglia ML, Donadio P. Ovarian tumors in children. Pediatr Med Chir. 1996;18(2):151-4.
Pliskow S. Endodermal sinus tumor of the ovary: review of 10 cases. South Med J. 1993;86(2):187-9. doi: 10.1097/00007611-199302000-00009
Guillem V, Poveda A. Germ cell tumours of the ovary. Clin Transl Oncol. 2007;9(4):237-43. doi: 10.1007/s12094-007-0045-0
Zamani N, Rezaei Poor M, Ghasemian Dizajmehr S, Alizadeh S, Modares Gilani M. Fertility sparing surgery in malignant ovarian Germ cell tumor (MOGCT): 15 years experiences. BMC Womens Health. 2021;21(1):282. doi: 10.1186/s12905-021-01437-8
Benradi L, El Haissoufi K, Ammor A, Benmoussa Y, Kamaoui I, Haloui A, et al. Mixed ovarian germ cell tumor in a child: A case report of a rare association. Ann Med Surg (Lond). 2021;65:102237. doi: 10.1016/j. amsu.2021.102237
Graham R, MacDonald ND, Lockley M, Miller R, Butler J, Murali K, et al. Surgical management and outcomes for stage 1 malignant ovarian germ cell tumours: A UK multicentre retrospective cohort study. Eur J Obstet Gynecol Reprod Biol. 2022 Apr;271:138-144. doi: 10.1016/j. ejogrb.2022.02.013
Instituto Nacional de Salud del Nino San Borja. Guia de Practica Clinica Masas Anexiales Benignas en Ginecologia Infanto Juvenil-GPC-003[Internet]. Lima: INSN SB; 2016. Disponible en: https://www.insnsb.gob.pe/guias-de-practica-clinicas/
Perez-Ortiz V, Reyna-Villasmil E. Tumor maligno mixto de células germinales de ovario. Reporte de caso. Rev Peru Ginecol Obstet. 2020;66(1):107-11. doi: 10.31403/rpgo.v66i2241
Elgendy A, Mostafa M, Salem MA, Ali A, Khairi A, Shehata S. Surgical resection and outcome of malignant ovarian germ cell tumors in children-a national multicentric study compared to international results. Pediatr Surg Int. 2020;36(9):1067-75. doi: 10.1007/s00383-020-04716-x
Perez-Ortiz V, Reyna-Villasmil E. Tumor maligno mixto de células germinales de ovario. Reporte de caso. Rev Peru Ginecol Obstet. 2020;66(1):107-11. doi: 10.31403/rpgo.v66i2241